Dave Asprey: ‘Biohacking the Vagus Nerve: The Ultimate Hack for Resilience and Brain Health’

Dave Asprey is the founder of Bulletproof and Upgrade Labs and is considered one of the pioneers of the biohacking movement. He is a four-time New York Times bestselling author focused on helping people extend their healthspan and optimize performance.

Health and wellness entrepreneur Dave Asprey has emphasized the significance of stimulating the vagus nerve to enhance resilience and brain function. In a recent blog post, Asprey explained, “The vagus nerve controls the parasympathetic nervous system, which helps regulate the body’s ‘rest-and-digest’ response.” He noted that activating this nerve can calm the fight-or-flight system, thereby reducing stress and inflammation.

Asprey highlighted traditional methods for stimulating the vagus nerve, stating, “Ancient cultures used deep breathing, chanting, yoga, and cold exposure to activate the vagus nerve.” He also pointed to modern technological advancements that can enhance these effects.

The vagus nerve plays a crucial role in connecting the brain to various organs, influencing functions such as heart rate, digestion, and emotional balance. Research published in Frontiers in Neuroscience has shown that vagus nerve stimulation may help regulate mood and inflammatory response, potentially benefiting individuals with depression and autoimmune conditions. Other studies suggest that vagal tone is linked to mental clarity, stress regulation, and faster recovery from physical exertion.

The FDA has approved vagus nerve stimulation devices for treatment of epilepsy and depression, and newer non-invasive tools are now available for home use. These tools aim to deliver similar benefits through electrical stimulation of the ear or neck areas that connect to vagal pathways.

Dave Asprey, often referred to as the “father of biohacking,” is the founder of Bulletproof and author of multiple books on health optimization. He is known for promoting the use of science, technology, and lifestyle interventions to extend lifespan and enhance cognitive and physical performance. Asprey has said his mission is to upgrade human biology using evidence-based methods and personal experimentation.