Mark Hyman, MD: ‘Protein sends your cells a biochemical message: you’re safe, you’re stable, you’re nourished’

Mark Hyman, MD, is a functional medicine doctor and bestselling author who promotes regenerative health and nutrition. He is known for advocating food systems reform and holistic strategies to restore planetary and human health.

In a recent post, functional medicine physician Dr. Mark Hyman highlighted protein’s critical role in brain function and emotional regulation, especially when consumed in the morning.

“Protein is one of the most powerful regulators of your nervous system,” said Dr. Hyman in a post on X. “What you eat in the morning directly influences your brain chemistry, your cravings, and your ability to regulate your nervous system throughout the day.”

He explained that cravings and emotional eating often result from a dysregulated brain-body system, typically triggered by disrupted dopamine signaling, unstable blood sugar, and chronic stress. Protein, by contrast, helps stabilize these systems by providing tyrosine—an amino acid essential for dopamine production.

Hyman referenced a randomized study involving late-adolescent girls who typically skipped breakfast. Those who consumed a high-protein breakfast (35g) experienced reduced cravings, fewer episodes of late-night snacking, and higher levels of homovanillic acid (HVA), a key dopamine metabolite. Low or blunted dopamine, he noted, often leads to compensatory eating behaviors in an attempt to restore neurochemical balance.

Dr. Hyman emphasized that eating enough protein, especially early in the day, sends a biochemical signal to the body that it is safe, nourished, and does not need to seek out hyper-palatable foods to cope with stress or low energy.

Hyman is a bestselling author, practicing physician, and thought leader in the field of functional medicine. His work centers on addressing root causes of chronic disease through nutrition, lifestyle, and integrative strategies.

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